THE EFFECTIVENESS OF ORAL SUCROSE ON PAIN DURING INVASIVE PROCEDURES IN PREMATURE INFANTS: SCOPING REVIEW

Kamilah Hayatun  Nufus; Adinda  Salsabilah; Nurul  Aeni; Zakiyyah Arief  Atshillah; Casman Casman

doi:10.47522/jmk.v1iIAHSC.111

Authors

Kamilah Hayatun Nufus STIKes RS Husada
Adinda Salsabilah STIKes RS Husada
Nurul Aeni STIKes RS Husada
Zakiyyah Arief Atshillah STIKes RS Husada
Casman Casman STIKes RS Husada

DOI:

https://doi.org/10.47522/jmk.v1iIAHSC.111

Keywords:

Oral sucrose, Pain of invasive procedure, Premature infant

Abstract

Introduction: Nowadays premature births continue to be common, it caused the infant necessitating treatment. Invasive procedures, such as the placement of an peripheral intravenous catheters or the drawing of blood, should be carried out while the baby is being cared for. Some intervention needed, sucrose is one approach to make invasive procedure less painful. This study aims to determine the effectiveness of oral sucrose in reducing the pain of invasive procedures in premature infants.

Method: This study is a scoping review, and 11 articles were selected from Proquest, ScienceDirect, Willy Online, PubMed, and EBSCO (CINAHL) databases.

Results: In eight of the articles, giving oral sucrose two minutes before the invasive procedure was effective in reducing pain, while sucrose was not effective in reducing pain in infants in the other three of the articles, during or after procedures.

Conclusion: According to these studies, giving oral sucrose to premature infant before invasive procedure is significant reducing the pain during invasive procedure.

Author Biographies

Kamilah Hayatun Nufus, STIKes RS Husada

Diploma of Nursing Program

Adinda Salsabilah, STIKes RS Husada

Diploma of Nursing Program

Nurul Aeni, STIKes RS Husada

Diploma of Nursing Program

Zakiyyah Arief Atshillah, STIKes RS Husada

Diploma of Nursing Program

Casman Casman, STIKes RS Husada

Instructor Of Pediatric Nursing

References

Asadi-Noghabi, F., Tavassoli-Farahi, M., Yousefi, H., & Sadeghi, T. (2014). Neonate pain management: what do nurses really know? Global Journal of Health Science, 6(5), 284–293. https://doi.org/10.5539/gjhs.v6n5p284

Beheshtipoor, N., Memarizadeh, A., Hashemi, F., Porarian, S., & Rambod, M. (2014). No Title. The Effect of Kangaroo Care on Pain and Physiological Parameters in Preterm Infants on Heel-Stick Procedure: A Randomized Controlled Crossover Study, 2 (4), 157–168.

Cook, L. M., Nichols-dada, J., Damani, S., Lawrence, V., Layson, S., Mitchell, D., Muhammad, S., Samaniego-yamin, L., Talley, J. W., VanNatta, B., Higgins, M., & Cooley, K. (2017). Randomized clinical trial of 24 % oral sucrose to decrease pain associated with peripheral intravenous catheter insertion in preterm and term newborns. Advances in Neonatal Care, 17(1), 3–11. https://doi.org/10.1097/ANC.0000000000000326

Fitri, S. Y. R., Lusmilasari, L., Juffrie, M., & Bellieni, C. V. (2020). Modified sensory stimulation using breastmilk for reducing pain intensity in neonates in indonesia: a randomized controlled trial. Journal of Pediatric Nursing, 53, e199–e203. https://doi.org/10.1016/j.pedn.2020.04.004

Gao, H., Li, M., Gao, H., Xu, G., Li, F., Zhou, J., Zou, Y., & Jiang, H. (2018). Effect of non-nutritive sucking and sucrose alone and in combination for repeated procedural pain in preterm infants: A randomized controlled trial. International Journal of Nursing Studies, 83(August 2017), 25–33. https://doi.org/10.1016/j.ijnurstu.2018.04.006

Gooding, L. F. (2010). Using music therapy protocols in the treatment of premature infants: An introduction to current practices. 37, 211–214.

Gouin, S., Gaucher, N., Lebel, D., & Desjardins, M. P. (2018). A randomized double-blind trial comparing the effect on pain of an oral sucrose solution vs. Placebo in children 1 to 3 months old undergoing simple venipuncture. The Journal of Emergency Medicine, 54(1), 33–39. https://doi.org/10.1016/j.jemermed.2017.08.015

Hastuti, W., Pujiwati, S., & Apriliyanti, R. (2021). Pemberian air susu ibu (ASI) dan dextrose 5 % untuk mengurangi nyeri pemasangan infus pada neonatus (breast milk and dextrose 5 % to reduce the pain of infusion in neonates). Jurnal Ilmu Keperawatan Maternitas, 3(1).

Hatfield, L. A., Gusic, M. E., Dyer, A.-M., & Polomano, R. C. (2008). Analgesic properties of oral sucrose during routine immunizations at 2 and 4 months of age. Pediatrics. https://doi.org/10.1542/peds.2006-3719.

Hockenberry, M. J., & Wilson, D. (2011). Wong’s Clinical Manual of Pediatric Nursing.

Kemenkes RI. (2018). Hasil Riset Kesehatan Dasar Tahun 2018. Kementrian Kesehatan RI, 53(9), 1689–1699.

Kementerian Pemberdayaan Perempuan dan Perlindungan Anak dan Badan Pusat Statistik. (2019). Profil Anak Indonesia Tahun 2019. Kementerian Pemerdayaan Perempuan Dan Perlindngan Anak (KPPPA), 378.

Kristoffersen, L., Malahleha, M., Duze, Z., Tegnander, E., Kapongo, N., Stoen, R., Follestad, T., Eik-Nes, S. H., & Bergseng, H. (2018). Randomised controlled trial showed that neonates received better pain relief from a higher dose of sucrose during venepuncture. Acta Paediatrica, 107, 2071–2078. https://doi.org/10.1111/apa.14567

Kubala, J. (2018). Sucrose Is Made up of Glucose and Fructose. 3 Juni. https://www.healthline.com/nutrition/sucrose-glucose-fructose#what-are-they?

Kyle, T., & Carman, S. (2014). Buku Praktik Keperawatan Pediatri. ECG.

Liaw, J.-J., Yang, L., Lee, C.-M., Fan, H.-C., Chang, Y.-C., & Cheng, L.-P. (2013). Effects of combined use of non-nutritive sucking, oral sucrose, and facilitated tucking on infant behavioural states across heel-stick procedures: a prospective, randomised controlled trial. https://doi.org/10.1016/j.ijnurstu.2012.08.021.

Passariello, A., Montaldo, P., Palma, M., Cirillo, M., Guida, C. Di, Esposito, S., Caruso, M., Pugliese, M., & Giliberti, P. (2019). Neonatal painful stimuli: skin conductance algesimeter index to measure efficacy 24 % of sucrose oral solution. The Journal of Maternal-Fetal & Neonatal Medicine, 0(0), 1–6. https://doi.org/10.1080/14767058.2019.1580690

Potter, P, A., & Perry, A. (2016). Fundamental Keperawatan, Konsep, Klinis dan Praktik. Penerbit Buku Kedokteran EGC.

Rustina, Y. (2015). Bayi prematur: Perspektif keperawatan. CV Sagung Seto.

Sen, E., & Manav, G. (2020). Effect of kangaroo care and oral sucrose on pain in premature infants: A randomized controlled trial. Pain Management Nursing, 21(6), 556–564. https://doi.org/10.1016/j.pmn.2020.05.003

Setiaji, R. B. R. (2020). Sama-Sama Gula, Tapi Apa Bedanya Sukrosa, Glukosa, Fruktosa? 18 Desember. https://hellosehat.com/nutrisi/fakta-gizi/beda-jenis-gula-sukrosa-glukosa-fruktosa/

Shah, S. R., Kadage, S., & Sinn, J. (2017). Trial of music, sucrose, and combination therapy for pain relief during heel prick procedures in neonates. The Journal of Pediatrics, 190, 153-158.e2. https://doi.org/10.1016/j.jpeds.2017.08.003

Shukla, V., Chapla, A., Uperiya, J., Nimbalkar, A., Phatak, A., & Nimbalkar, S. (2018). Sucrose vs. skin to skin care for preterm neonatal pain control — a randomized control trial. Journal of Perinatology, June 2017, 1–5. https://doi.org/10.1038/s41372-018-0193-9

Tamsuri, A. (2015). Konsep dan Penatalaksanaan Nyeri. Penerbit Buku Kedokteran EGC.

Widayati, F., Arief, Y. S., Pradanie, R., Studi, P., Ners, P., Keperawatan, F., & Airlangga, U. (1996). Peningkatan patensi pemasangan iv line pada neonatus dengan penggunaan elastic bandage. 031.

Willis, M. H. W., Merkel, S. I., Voepel-Lewis, T., & Malviya, S. (2003). FLACC behavior pain assessment scale: Acomparrison with the child’s selfreport.

World Health Organization. (2018). Preterm Birth. 19 Februari. https://www.who.int/news-room/fact-sheets/detail/preterm-birth

World Health Organization. (2019). Low BirthWeight. Mei. https://data.unicef.org/topic/nutrition/low-birthweight/

Wulandari, R. (2011). Peran Perawat Anak terhadap Prinsip Perawatan Atraumatik Pada Anak. Peran Perawat Anak Terhadap Prinsip Perawatan Atraumatik Pada Anak, 8.

Zakiyah, A. (2015). Nyeri Konsep dan Penatalaksanaan Dalam Praktik Keperawatan Berbasis Bukti. Salemba Medika